Synthesis of 5-Bromovanillin , Room Temperature Bromination

Combine 30.4 g of vanillin, 150 mL of glacial acetic acid and 35.2 g (11.4 mL) of bromine. Stir for 1h, pour the mixture into 200 mL of water ice mixture, filter, wash the precipitate with water 3 times. Dry the 5-bromovanillin and recrystallize in hot ethanol.


Filtering and washing the precipitate

Scroll to top