Synthesis of 1-Octanethiol

To a reflux apparatus add 32.5 g of 1-bromooctane, 80 mL of ethanol and 12.5 g of thiourea, reflux the mixture for 3.5h and then add a solution of 10 g of sodium hydroxide dissolved in 30 mL of water and reflux for additional 3.5h. The solution is cooled down, washed with 2.5 mL of sulfuric acid dissolved in 20 mL of water and with additional 20 mL of water. The organic layer is then dried over anhydrous magnesium sulfate and distilled in 196-201°C

riflusso

Refluxing the solution

becher

Washing the organic layer

margherite

The crude product drying over the drying agent

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